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| Started in 1434, design by Brunelleschi |
This was the first centralized building of the Renaissance, and it may have been inspired again by the ancient ruins in Rome, most likely the Temple of Minerva Medica. In the Sta. Maria there is a strong sense of symmetry, a longtime pursuit of Brunelleschi's. Moving away from the modular squares of San Croce, this building is more along the lines of the Santo Spirito with its sculptural tendencies. The rotunda shape has a sense of plasticity, it seems to be carved out of pre-existing material with molded interiors. Although this is a classically influenced structure, it maintains a refreshing vivacity.

